New & Second Hand Cannondale Synapse For Sale

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When it comes to finding the perfect partner for those long days in the saddle, look no further than the Cannondale Synapse line. Bridging the gap between all-day comfort and zippy road handling, these endurance machines have been refining the art of fast long-distance riding for decades.

Cannondale’s proprietary SAVE suspension technology keeps high-frequency vibrations from draining your power reserves mile after mile. Carefully crafted frame geometries fit a wide range of builds—from relaxed tours to aggressive centuries. Copious mounting points on select models allow adventurous bikepacking excursions off the beaten path.

Browse our collection of Synapse models below to find your ideal steed. Carbon and aluminium options cover a variety of performance levels and budgets. Gearing fits from gentle ascents to supersonic flats. Let these bikes transport you on riding holidays never-ending, with smiles intact thanks to their legendary smoothness. Your endurance will thank you as you cover ground that leaves others weary—because with a Synapse, fast and fun need never be mutually exclusive.